For example, ἐν or Ἐν are the same but should be distinguished from ἕν/Ἓν. I tried utf8_bin which seems to be the closest but is also case sensitive.
mysql> select 'ἐν' = 'Ἐν' collate utf8mb4_0900_as_ci; +----------------------------------------------+ | 'ἐν' = 'Ἐν' collate utf8mb4_0900_as_ci | +----------------------------------------------+ | 1 | +----------------------------------------------+ mysql> select 'ἐν' = 'ἕν' collate utf8mb4_0900_as_ci; +----------------------------------------------+ | 'ἐν' = 'ἕν' collate utf8mb4_0900_as_ci | +----------------------------------------------+ | 0 | +----------------------------------------------+