C’est difficile à expliquer. Mais je vais essayer, toute la toile est décalée. Je ne sais pas comment cela s'est produit ni comment y remédier. Comme lorsque votre souris se trouve dans le coin supérieur gauche de la page et que vous partez du centre, elle correspond au coin supérieur gauche de l'élément canevas lui-même. Utilisez des extraits de code pour comprendre de quoi je parle.

let currentColor = null;

let inputs = document.getElementsByClassName("style2");

for (const input of inputs) {
  input.addEventListener("click", (e) => {
    if (e.detail !== 2) e.preventDefault();
  });
}


let arr = [];

for (let i = 0; i < inputs.length + 1; i++) {
  arr.push(i.toString());
}
arr.shift();

for (const input of inputs) {
  input.addEventListener("input", (e) => {
    const { value } = document.getElementById(e.target.id);
    currentColor = value;
    $("#selectedColor").css("background-color", value);
  })
    input.addEventListener("click", (e) => {
    const { value }  = document.getElementById(e.target.id);
    currentColor = value;
    $("#selectedColor").css("background-color", value);
  })
}

var rangeslider = document.getElementById("sliderRange");
const setSize = document.getElementById("setSize")
const submit = document.getElementById("submit")

submit.addEventListener("click", (e) => {
  rangeslider.value = setSize.value 
})

const button = document.getElementById("clear")
// create canvas element and append it to document body
var canvas = document.getElementById('canvas');
// some hotfixes... ( ≖_≖)
// get canvas 2D context and set him correct size
var ctx = canvas.getContext('2d');
resize();

// last known position
var pos = { x: 0, y: 0 };

window.addEventListener('resize', resize);
button.addEventListener('click', clear)
document.addEventListener('mousemove', draw);
document.addEventListener('mousedown', setPosition);
document.addEventListener('mousemove', setPosition);


// new position from mouse event
function setPosition(e) {
  let canvas = document.getElementById("canvas")
  pos.x = e.clientX
  pos.y = e.clientY
}

// resize canvas
function resize() {
  ctx.canvas.width = 650;
  ctx.canvas.height = 375;
}

function draw(e) {
  // mouse left button must be pressed
  if (e.buttons !== 1) return;
  let canvas = document.getElementById('canvas');

  console.log(pos)
  ctx.beginPath(); // begin

  ctx.lineWidth = rangeslider.value;
  ctx.lineCap = 'round';
  ctx.strokeStyle = currentColor;

  ctx.moveTo(pos.x, pos.y); // from
  setPosition(e);
  ctx.lineTo(pos.x, pos.y); // to

  ctx.stroke(); // draw it!
}

function clear() {
  ctx.clearRect(0, 0, canvas.width, canvas.height);
}

html, body {
  height: 100%;
  width: 100%;
  font-family: sans-serif;
  background-color: #B3B7B5;
/*   overflow: hidden; */
}

.style2 {
  -webkit-appearance: none;
  -moz-appearance: none;
  appearance: none;
  background-color: transparent;
  width: 35px;
  height: 35px;
  border: none;
  cursor: pointer;
}


.style2::-webkit-color-swatch {
  border-radius: 50%;
  border: 3px solid #000000;
}
.style2::-moz-color-swatch {
  border-radius: 50%;
  border: 3px solid #000000;
}

.box {
  display: flex;
  flex-direction: row;
  flex-wrap: wrap;
  justify-content: center;
  align-items: center;
  gap: 5px;
  max-width: 320px;
  margin: 0 auto;
  padding: 7.5px 10px;
}

.box1 {
    display: flex;
  flex-direction: row;
  flex-wrap: wrap;
  justify-content: center;
  align-items: center;
  gap: 5px;
  max-width: 9999px;
  margin: 0 auto;
  padding: 10px 10px;
}

.box5 {
    display: flex;
  flex-direction: row;
  flex-wrap: wrap;
  justify-content: center;
  align-items: center;
  gap: 5px;
  max-width: 650px;
  margin: 0 auto;
  padding: 10px 10px;
}

.box2 {
  display: flex;
  flex-direction: row;
  flex-wrap: wrap;
  justify-content: center;
  align-items: center;
  gap: 5px;
  max-width: 9999px;
  margin: 0 auto;
  padding: 10px 10px;
}

#selectedColor {
  width: 100px;
  height: 30px;
  border: 3px solid black;
  border-radius: 5px;
  background-color: black;
}

.canvas {
  height: 350px;
  width: 650px;
  border: 3px solid black;
  border-radius: 5px;
  background-color: white;
  cursor: crosshair;
  position: relative;
/*   left: 50%; */
}

#clear {
  width: 50px;
  height: 35px;
  font-size: 15px;
  border-radius: 5px;
}

#submit {
  width: 59px;
  height: 23px;
  margin: auto;
  left: 35%;
  border-radius: 5px;
  position: relative;
}

.rangeslider {
    width: 50%;
}
  
.myslider {
    -webkit-appearance: none;
    background: #FCF3CF  ;
    width: 50%;
    height: 20px;
    opacity: 2;
   }
  
  
.myslider::-webkit-slider-thumb {
    -webkit-appearance: none;
    cursor: pointer;
    background: #34495E  ;
    width: 5%;
    height: 20px;
}
  
  
.myslider:hover {
    opacity: 1;
}

.rangeslider {
  left: 38%;
  position: absolute;
}

<!DOCTYPE html>
<html>

<head>
  <meta charset="utf-8">
  <meta name="viewport" content="width=device-width">
  <title>replit</title>
  <link href="style.css" rel="stylesheet" type="text/css" />
</head>

<body>
  <script src="https://ajax.googleapis.com/ajax/libs/jquery/2.1.1/jquery.min.js"></script>

  <div class="box5">
    <canvas class="canvas" id="canvas"></canvas>
  </div>
  
  <div class="box1">
    <button id="clear">Clear</button><br>
  </div>

  <div class="box1">
    <div class="rangeslider">
          <input type="range" min="1" max="100" value="5" class="myslider" id="sliderRange">
    </div>
  </div>
  <div class=box1>
    <div>
      <input id="setSize" type="text" placeholder="Set Brush Size... (Max 100)">
      <br>
      <button type="submit" id="submit" for="setSize">Submit</button>
    </div>
  </div>
  
  <div class="box">
      <div class="container">
        <input type="color" value="#000000" class="style2" id="1" />
      </div>
      <div class="container">
        <input type="color" value="#ffffff" class="style2" id="2" />
      </div>
      <div class="container">
        <input type="color" value="#ffffff" class="style2" id="3" />
      </div>
      <div class="container">
        <input type="color" value="#ffffff" class="style2" id="4" />
      </div>
      <div class="container">
        <input type="color" value="#ffffff" class="style2" id="5" />
      </div>
  </div>

  <div class="box">
    <label for="selectedColor">Current Color:</label>
    <div id="selectedColor"></div>
  </div>

  <script src="script.js"></script>
</body>

</html>
 

Je sais que ce code est un peu bizarre, mais faites-le-moi savoir.