Destiny 2: Revenant - Slayer Baron Apothecary Satchel Artifact Guide

A new Destiny 2 season means there's a new Artifact to unlock. Revenant brings with it the Slayer Baron Apothecary Satchel, featuring some fan-favorite perks and some powerful new Stasis-themed buffs. Relive the power of Breach and Clear, freeze the arena with Brain Freeze, or give all of your builds Devour with Power from Pain.

And as with Echoes, we'll be seeing frequent changes to the Artifact as the season continues. For the season's first Act, we're looking at 25 new perks to choose from, divided evenly between five columns. In this guide, we explain how the Artifact works, how to unlock it, and showcase the effects of all 30 perks.

Updated November 19, 2024, by Charles Burgar: The next five perks in the Artifact are now available to use in Act 2 of Revenant. We've updated the guide to include information on how these five new perks work.

How The Artifact Works In Episode: Revenant

Column One	Column Two	Column Three	Column Four	Column Five
Anti-Barrier Scout Rifle	One With Frost	Wind Chill	Armor of Eramis	Brain Freeze
Overload SMG	Killing Breeze	Crystalline Converter	Hail the Storm	Supernova
Unstoppable Pulse Rifle	Enhanced Ether Generator	Total Carnage	Debilitating Wave	Conductive Cosmic Crystal
Anti-Barrier Shotgun	Fell The Revenant	Power From Pain	Concussive Reload	Serve Cold
Overload Breechloaded Grenade Launcher	Rapid Impacts	Trace Evidence	Retinal Burn	Kinetic Impacts
Authorized Mods: Melee	Emergency Flare	The Thick Of It	Curative Orbs	Arc Compounding

The Slayer Baron Apothecary Satchel is unlocked through the starting mission in Episode: Revenant, which should start immediately upon login. All XP you earn throughout the episode will increase the Artifact's level, unlocking additional Artifact perks while increasing your account's Power level. The more XP you earn, the more perks and bonus Power you'll earn.

For the first two acts, the Artifact has 30 perks to choose from, broken up into five columns. You can find your Artifact in the character tab, the same place you equip weapons. The Artifact can only have 12 perks active at a time, separated by columns:

• Column One: Unlocked by default.
• Column Two: Requires 3 unlocked passives from the previous column.
• Column Three: Requires 5 unlocked passives from previous columns.
• Column Four: Requires 7 unlocked passives from previous columns.
• Column Five: Requires 10 unlocked passives from previous columns.

Resetting Your Artifact

While inspecting the Artifact, you can reset it by holding the "Reset Artifact" button. Doing so doesn't cost anything and refunds all spent points. You can reallocate your Artifact as many times as you please. The only exception is when you're in loadout-locked content like GM Nightfalls.

Column One Perks

Anti-Barrier Scout Rifle	Your equipped Scout Rifles pierce Barrier Champion shields. Additionally, Scout Rifles are always Overcharged when that modifier is active.
Overload SMG	Landing consecutive hits with an SMG will stun Overload Champions. Additionally, SMGs are always Overcharged when that modifier is active.
Unstoppable Pulse Rifle	Aiming down sights for a couple of seconds will load an explosive round, stunning Unstoppable Champions. Additionally, Pulse Rifles are always Overcharged when that modifier is active.
Anti-Barrier Shotgun	Shotguns fire shield-piercing rounds, strong against Barrier Champions. Additionally, Shotguns are always Overcharged when that modifier is active.
Overload Breechloaded Grenade Launcher	Damaging a combatant with a Special GL inflicts Overload, strong against Overload Champions. Additionally, Primary and Special GLs are always Overcharged when that modifier is active.
Authorized Mods: Melee	Armor mods that affect your melee ability now cost 1 energy.

Anti-Barrier Weapons gain shield-piercing capabilities, allowing them to pierce invulnerable shields on fodder units like Vex Hobgoblins, Hydras, and physical Cabal shields held by Phalanxes. Additionally, all Anti-Barrier weapons deal 20% more damage against Titan Barricades in the Crucible.

Overload Weapons gain the Overload effect with sustained damage—excluding Grenade Launchers, which gain it when you immediately swap to them. Damaging an enemy with an Overload round will decrease their outgoing damage for a short duration, and PvE enemies will be less likely to use abilities. Enemy Guardians also gain a small ability regeneration penalty while affected by Overload, but it's hardly noticeable.

Unstoppable Weapons load an explosive projectile when you ADS for a second. Firing this round inflicts guaranteed stagger on PvE enemies. It does not increase your damage output. Unstoppable rounds do nothing in PvP.

Authorized Mods: Melee sets the armor drain cost to one for the following melee mods: Hands-On, Heavy-Handed, Momentum Transfer, Focusing Strike, and Melee Kickstart. If you had these mods equipped before activating this Artifact perk, you'll need to re-equip them to receive the drain discount.

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