django - Python error: [Errno 99] Cannot assign requested address

Internal Server Error: /api/users/
Traceback (most recent call last):
  File "/usr/local/lib/python2.7/dist-packages/django/core/handlers/exception.py", line 41, in inner
    response = get_response(request)
  File "/usr/local/lib/python2.7/dist-packages/django/core/handlers/base.py", line 187, in _get_response
    response = self.process_exception_by_middleware(e, request)
  File "/usr/local/lib/python2.7/dist-packages/django/core/handlers/base.py", line 185, in _get_response
    response = wrapped_callback(request, *callback_args, **callback_kwargs)
  File "/usr/local/lib/python2.7/dist-packages/django/views/decorators/csrf.py", line 58, in wrapped_view
    return view_func(*args, **kwargs)
  File "/usr/local/lib/python2.7/dist-packages/rest_framework/viewsets.py", line 86, in view
    return self.dispatch(request, *args, **kwargs)
  File "/usr/local/lib/python2.7/dist-packages/rest_framework/views.py", line 489, in dispatch
    response = self.handle_exception(exc)
  File "/usr/local/lib/python2.7/dist-packages/rest_framework/views.py", line 449, in handle_exception
    self.raise_uncaught_exception(exc)
  File "/usr/local/lib/python2.7/dist-packages/rest_framework/views.py", line 486, in dispatch
    response = handler(request, *args, **kwargs)
  File "/usr/local/lib/python2.7/dist-packages/misago/users/api/users.py", line 78, in create
    return create_endpoint(request)
  File "/usr/local/lib/python2.7/dist-packages/django/utils/decorators.py", line 149, in _wrapped_view
    response = view_func(request, *args, **kwargs)
  File "/usr/local/lib/python2.7/dist-packages/misago/users/api/userendpoints/create.py", line 68, in create_endpoint
    mail_user(request, new_user, mail_subject, 'misago/emails/register/complete')
  File "/usr/local/lib/python2.7/dist-packages/misago/core/mail.py", line 22, in mail_user
    message.send()
  File "/usr/local/lib/python2.7/dist-packages/django/core/mail/message.py", line 348, in send
    return self.get_connection(fail_silently).send_messages([self])
  File "/usr/local/lib/python2.7/dist-packages/django/core/mail/backends/smtp.py", line 104, in send_messages
    new_conn_created = self.open()
  File "/usr/local/lib/python2.7/dist-packages/django/core/mail/backends/smtp.py", line 64, in open
    self.connection = self.connection_class(self.host, self.port, **connection_params)
  File "/usr/lib/python2.7/smtplib.py", line 256, in __init__
    (code, msg) = self.connect(host, port)
  File "/usr/lib/python2.7/smtplib.py", line 316, in connect
    self.sock = self._get_socket(host, port, self.timeout)
  File "/usr/lib/python2.7/smtplib.py", line 291, in _get_socket
    return socket.create_connection((host, port), timeout)
  File "/usr/lib/python2.7/socket.py", line 575, in create_connection
    raise err
error: [Errno 99] Cannot assign requested address

google没有找到对应的问题啊，py新人求助~~