範囲クエリを使用する複数列インデックスでは、カーディナリティの高い列を最初に置く必要がありますか?

CREATE TABLE `files` (
  `did` int(10) unsigned NOT NULL DEFAULT '0',
  `filename` varbinary(200) NOT NULL,
  `ext` varbinary(5) DEFAULT NULL,
  `fsize` double DEFAULT NULL,
  `filetime` datetime DEFAULT NULL,
  PRIMARY KEY (`did`,`filename`),
  KEY `fe` (`filetime`,`ext`),          -- This?
  KEY `ef` (`ext`,`filetime`)           -- or This?
) ENGINE=InnoDB DEFAULT CHARSET=utf8 ;

-- Forcing the range on filetime first
mysql> EXPLAIN SELECT COUNT(*), AVG(fsize)
    FROM files FORCE INDEX(fe)
    WHERE ext = 'gif' AND filetime >= '2015-01-01'
                      AND filetime <  '2015-01-01' + INTERVAL 1 MONTH;

-- Forcing the low-cardinality ext first
mysql> EXPLAIN SELECT COUNT(*), AVG(fsize)
    FROM files FORCE INDEX(ef)
    WHERE ext = 'gif' AND filetime >= '2015-01-01'
                      AND filetime <  '2015-01-01' + INTERVAL 1 MONTH;

"potential_range_indices": [
    ...
    {
        "index": "fe",
        "usable": true,
        ...
    },
    {
        "index": "ef",
        "usable": true,
        ...
    }
],
"analyzing_range_alternatives": {
    "range_scan_alternatives": [
        {
            "index": "fe",
            "ranges": [
                "2015-01-01 00:00:00 <= filetime < 2015-02-01 00:00:00"
            ],
            "cost": 20022,   -- Higher cost
        },
        {
            "index": "ef",
            "ranges": [
                "gif <= ext <= gif AND 2015-01-01 00:00:00 <= filetime < 2015-02-01 00:00:00"
            ],
            "cost": 646.61,  -- Lower cost
        }
    ],
}